Tag Archives: statins

Concerning Blood Pressure

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The Great Blood Pressure Scam

Exploring the Forgotten Causes and Treatments of Hypertension and the Dangers of BP Medications

A MIDWESTERN DOCTOR
JUL 29, 2024

Story at a Glance:

•Elevated blood pressure is the most common chronic disease, and as the decades go by more and more people are declared hypertensive.

•Remarkably, at least 25% of all hypertension diagnoses are due to inaccurate measurements, and there is still no known reason for why over 90% of people are hypertensive.

•Aggressively treating everyone’s blood pressure is justified under the belief it prevents cardiovascular disease. However, in most cases it has never been proven to reduce heart disease—rather it only leads to a small reduction in strokes (hence why these medications were rebranded to treat “cardiovascular disease”).

•Many of the misunderstandings with heart disease arise from the fact that impaired circulation or damage to the blood vessels will cause blood pressure to go up and their correlation being misinterpreted to instead believe high blood pressure causes cardiovascular disease.

•In this article, we will discuss the actual causes of high blood pressure, the dangers of commonly used blood pressure medications, the safest pharmaceutical and natural ways to reduce blood pressure directly, and our preferred methods for treating the underlying causes of high blood pressure.

Ever since I first encountered the medical field, something struck me as off about their relentless focus on blood pressure. Before long, I began to notice that the blood pressures the same acquaintances (e.g., relatives or friends) shared with me varied immensely. As I was pondering this, a long-time Eastern spiritual teacher shared with me their belief that the West’s relentless focus on blood pressure was due to it being much easier to measure than blood perfusion (healthy blood flow).

Then, as I became more acquainted with the medical field, I began to notice a consistent pattern—whenever a drug existed that could treat a number or statistic, as the years went by, the acceptable number kept on being narrowed, making more and more people eligible to take the drugs that treated the number.

For example, as I discussed recently, once the statins drugs entered the market (which unlike their predecessors, could effectively lower cholesterol), the acceptable blood cholesterol levels kept on being lowered, and before long almost everyone was told they would die from a heart attack unless they started a statin—despite statins have an almost non-existing mortality benefit (e.g., taking them for 5 years at best makes you live 3-4 days longer) and causing (often severe) side effects for roughly 20% of users. Broadly recommending these drugs hence appears unconscionable, but as I showed in that article, these unjustifiable guidelines were a product of clever pharmaceutical marketing and targeted bribery of public officials.

In this article, I will attempt to show how something similar happened in the field of blood pressure. As this is an immensely controversial position to take (e.g., measuring and documenting blood pressure is one of the most routine procedures during a medical visit), I’ve done my best to clearly present the evidence for this perspective so you can make your own determination.

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Cholesterol, Statins, & Heart Disease

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This is a highly abbreviated version of the total article.  Go to the Link (https://www.midwesterndoctor.com/p/the-great-cholesterol-scam-and-the?publication_id=748806&post_id=146062962&isFreemail=true&r=19iztd&triedRedirect=true&utm_source=substack&utm_medium=email) to read the rest:

 

The Great Cholesterol Scam and The Dangers of Statins

Exploring the Actual Causes and Treatments of Heart Disease

A MIDWESTERN DOCTOR
JUN 30, 2024

Story at a Glance:

•There is a widespread belief that elevated cholesterol is the “cause” of cardiovascular disease. However, a large body of evidence shows that there is no association between the two and that lower cholesterol significantly increases one’s risk of death.

•An alternative model (which the medical industry buried) proposes that the blood clots the body uses to heal arterial damage, once healed, create the characteristic atherosclerotic lesions associated with heart disease. The evidence for this model, in turn, is much stronger than the cholesterol hypothesis and provides many important insights for treating heart disease.

•The primary approach to treating heart disease is to prescribe cholesterol lowering statin drugs (to the point, over a trillion dollars have now been spent on them). Unfortunately, the benefits of these highly toxic drugs are minuscule (e.g., at best taking them for years extends your life by a few days) and the harms are vast (statins are one of the most common pharmaceuticals that severely injure patients).

•In this article we will explore the specific injuries caused by statin drugs, the forgotten causes of cardiovascular disease, and our preferred treatments for heart and vascular diseases.

The more I study science, the more I come to see how often fundamental facts end up being changed so that a profitable industry can be created. In the case of heart disease, I very much believe that is the case and in this publication, I’ve tried to expose the erroneous information that predominates our understanding of this subject (e.g., previously I’ve discussed why our model of how the heart pumps blood in the body is incorrect and in an article that will be released in a few weeks, I will detail the major misconceptions about blood pressure management).

Within cardiology, I believe one of the most damaging falsehoods is that cholesterol causes heart disease and that taking statins (or their newer equivalents), which lower cholesterol, are the key to preventing heart disease. This is because, in addition to those “facts” being incorrect, statins are also some of the most dangerous and widely used pharmaceutical drugs on the market.

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Cholesterol and Heart Disease

Frequently, when an industry harms many people, it will create a scapegoat to get out of trouble. Once this happens, a variety of other sectors that also benefit from that scapegoat existing will jump on the bandwagon. Before long, a false belief that harms society becomes an unquestionable dogma that becomes very difficult to overturn because many corrupt parties have a vested interest in maintaining the lie.

For example, various easily addressable factors (which often exist in the first place because they benefit an industry) are responsible for the chronic diseases we face in society and our vulnerability to infectious diseases (e.g., the obese and diabetics were much more likely to catch COVID-19). However, by saying all diseases result from insufficient vaccination, it gets all those destructive industries off the hook and creates a huge market for selling vaccines and treatments for these illnesses. Thus, since there are so many vested interests behind the vaccine paradigm, it is very difficult to overturn—despite the fact the existing evidence shows vaccinations are responsible for the massive epidemic of chronic disease that is sweeping our country.

In the 1960s and 1970s, a debate emerged over what caused heart disease. On one side, John Yudkin effectively argued that the sugar being added to our food by the processed food industry was the chief culprit. On the other side, Ancel Keys (who attacked Yudkin’s work) argued that it was due to saturated fat and cholesterol.

Note: a case can also be made that the mass adoption of vegetable oils lead to this increase in heart disease. Likewise, some believe the advent of water chlorination was responsible for this increase.

Ancel Keys won, Yudkin’s work was largely dismissed, and Keys became nutritional dogma. A large part of Key’s victory was based on his study of seven countries (Italy, Greece, Former Yugoslavia, Netherlands, Finland, America, and Japan), which showed that as saturated fat consumption increased, heart disease increased in a linear fashion.

However, what many don’t know (as this study is still frequently cited) is that this result was simply a product of the countries Keys chose (e.g., one author illustrated that if Finland, Israel, Netherlands, Germany, Switzerland, France, and Sweden had been chosen, the opposite would have been found).

Fortunately, it gradually became recognized that Ancel Keys did not accurately report the data he used to substantiate his arguments. For example, recently an unpublished 56 month randomized study of 9,423 adults living in state mental hospitals or a nursing home (which made it possible to rigidly control their diets) that Keys was the lead investigator of was unearthed. This study (inconveniently) found that replacing half of the animal (saturated) fats they ate with vegetable oil (e.g., corn oil) lowered their cholesterol, and that for every 30 points it dropped, their risk of death increased by 22 percent (which roughly translates to each 1% drop in cholesterol raising the risk of death by 1%)—so as you can imagine, it was never published.

Note: the author who unearthed that study also discovered another (unpublished) study from the 1970s of 458 Australians, which found that replacing some of their saturated fat with vegetable oils increased their risk of dying by 17.6%

Likewise, recently, one of the most prestigious medical journals in the world published internal sugar industry documents. They showed the sugar industry had used bribes to make scientists place the blame for heart disease on fat so Yudkin’s work would not threaten the sugar industry. In turn, it is now generally accepted that Yudkin was right, but nonetheless, our medical guidelines are still largely based on Key’s work.

However, despite a significant amount of data that now shows lowering cholesterol is not associated with a reduction in heart disease (e.g., this study, this study, this study, this review, this review, and this review) the need to lower cholesterol is still a dogma within cardiology. For example, how many of you have heard of this 1986 study which was published in the Lancet which concluded:

During 10 years of follow-up from Dec 1, 1986, to Oct 1, 1996, a total of 642 participants died. Each 1 mmol/L increase in total cholesterol corresponded to a 15% decrease in mortality (risk ratio 0–85 [95% Cl 0·79–0·91]).

Note: when people are diabetic (which leads to the liver having to process too much sugar) the liver will convert to fat and then create more cholesterol to transport some of that fat. In these instances, I would argue the actual issue is an excess of sugar rather than elevated cholesterol levels it causes.

Statins Marketing

One of the consistent patterns I’ve observed within medicine is that once a drug is identified that can “beneficially” change a number, medical practice guidelines will gradually shift to prioritizing treating that number and before long, rationals will be created that require more and more of the population to be subject to that regimen. In the case of statins, prior to their discovery, it was difficult to reliably lower cholesterol, but once they hit the market, research rapidly emerged stating that cholesterol was more and more dangerous and, hence that more and more people needed to be on statins.  …

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Heart Health, Statins, Fats, etc.

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Great Britain’s Most Outspoken Cardiologist Sets the Record Straight on Saturated Fats

June 05, 2016

By Dr. Mercola

Is saturated fat really the health hazard it’s been made out to be? Dr. Aseem Malhotra is an interventional cardiologist consultant in London, U.K., who gained quite a bit of publicity after the publication of his peer-reviewed editorial1 in the British Medical Journal (BMJ) in 2013.

In it, he seriously challenges the conventional view on saturated fats, and reviews how recent studies have failed to find any significant association between saturated fat and cardiovascular risk.

In fact, Malhotra reports that two-thirds of people admitted to hospitals with acute myocardial infarction have completely normal cholesterol levels. Malhotra, founder of Action on Sugar, also works as an adviser to the U.K.’s National Obesity Forum.

“My focus has been, ‘what can we do as individuals collectively (the medical profession) to help curb demand on the health system?’” he says. “A lot of that is being driven by diet-related diseases.

According to the Lancet Global Burden of Disease Reports, poor diets now contribute to more disease and death than physical activities — smoking and alcohol combined …

As an interventional cardiologist, we can do life-saving procedures with people who have heart attacks through heart surgery. But to be honest, rather than saving them from drowning, I’d rather they wouldn’t be thrown into the river in the first place. This is really where my focus has shifted.

I think for many of us, as clinicians moving more towards intervention, I think the realization that what we can do in medicine is really quite limited at the treatment end and actually the whole ‘prevention is better than cure’ phrase is very true.”

Hospitals and Medical Personnel Are Far From Paragons of Health

Malhotra’s epiphany that something was wrong with the system came rather early. While working as a resident in cardiology, he performed an emergency stenting procedure on a man in his 50s who’d recently suffered a heart attack.

The following morning, Malhotra spoke to the man, giving him the usual advice about quitting smoking and improving his diet.

“Just when I was telling about healthy diet, how important that was, he was actually served burger and fries by the hospital. He said to me, ‘Doctor, how do you expect me to change my lifestyle when you’re serving me the same crap that brought me in here in the first place?’”

Looking around, he realized that a lot of healthcare professionals are overweight or obese, and hospitals serve sick patients junk food. He believes one of the first things that really needs to happen is to set a good example in hospitals.

“The hospital environment should be one that promotes good health, not exacerbates bad health,” he says. His journey began with an email to celebrity chef Jamie Oliver, who did a lot of work campaigning for improved food in school canteens. Malhotra asked Oliver for ideas on how to improve hospital food.

“A couple of years later, I ended up going to the British Medical Association Annual Conference. I put a motion forward saying there should be a policy from the BMA to ban the selling of junk food in hospitals. It got an overwhelming majority vote.”

Diet and lifestyle changes are particularly important in light of the fact that medical errors and properly prescribed medications are the third most common cause of death after heart disease and cancer. Overmedication is a particularly serious problem among the elderly, who tend to suffer more side effects.

“Part of that is because there are very powerful vested interests that push drugs,” Malhotra says. “They even coax academic institutions and guideline bodies. People aren’t getting all the information to make decisions, whether or not they should take medications …

This is a major problem, especially [since] we’ve neglected or detracted from lifestyle changes, which are going to be much more impactful on your health and without side effects.”

For Past 60 Years, the Wrong Fats Have Been Vilified

For the past 60 years, the conventional wisdom has dictated that saturated fat is dangerous and should be avoided. This flawed notion was originally promoted by Dr. Ancel Keys, whose Seven Countries Study laid the groundwork for the myth that saturated fat caused heart disease.

It’s true that heart disease rates began spiking in the beginning of the 20th century, and for 50 years, heart disease has been progressively increasing. It really wasn’t an issue prior to the 20th century. But were saturated fats really to blame?

My belief is that it was in fact due to fats, but contrary to popular belief, saturated fat wasn’t the problem. It was all the other harmful fats people were eating.

In the 20th century, the average person probably had less than 1 pound a year of refined, processed omega-6 vegetable oils. By the 1950s, probably about 50 pounds a year, and by year 2000, it increased at about 75 pounds a year. It seems “fat” in itself isn’t the issue; it’s the type of fat that’s crucial.

This massive amount of highly refined polyunsaturated fat is far in excess of what we were designed to eat for optimal health. And I suspect that’s what catalyzed Keys to devise his research to come up with a justification for his recommendation to lower fat intake.

“What’s interesting is if you look in the United States, between 1961 and 2011, 90 percent of the calorie intake has been carbohydrates and refined industrial vegetable oils,” Malhotra says. “I think you’re absolutely correct.

The heart disease epidemic peaked between 1960 and 1970. It started to rise about 1920. When we look at our data, it’s quite clear that the so-called fats responsible for that are trans fats and very likely polyunsaturated vegetable oils high in omega-6 fatty acids.

We know now that they oxidize LDL and are pro-inflammatory. The other issue was smoking. Smoking was very high. When smoking reduction occurred from regulatory efforts, heart attack admissions dropped very rapidly. That’s because just 30 minutes after smoking, platelet activity increases.

A quick example: Helena, Montana 2002 brought in a public smoking ban. Within six months, there was a 40 percent reduction in hospital admissions for heart attack. When the law was rescinded, the hospital admissions came back to preceding levels.

When you combine all those things, it’s very clear. The dietary factors — trans fats, refined polyunsaturated vegetable oils, and smoking — are probably the three most important factors.”

What Are the Real Risk Factors for Heart Disease?

By failing to differentiate between trans fats and saturated fats, massive confusion has arisen. There’s also confusion about the relationship between saturated fat and cholesterol. Adding to the complexity, there are also different types of saturated fats, which may have different biological effects.

Many saturated fats will raise LDL, the so-called “bad” cholesterol. But LDLs come in various sizes. Large type A particles are less atherogenic and are influenced by saturated fat. Saturated fat also increases HDL, the “good” cholesterol.

“What’s interesting is the saturated fat, even though it may raise LDL, your lipid profile may actually improve [when you eat more saturated fat], especially when you cut the carbs. On top of that, LDL has been grossly exaggerated as a risk factor for heart disease, with the exception of people who have a genetic abnormality (familial hypercholesterolemia),” Malhotra says.

“Certainly when you get over the age of 60, the cardiovascular association between LDL cholesterol and cardiovascular mortality diminishes. It becomes almost negligible. For overall mortality, there is an inverse association with LDL. The higher your LDL, if you’re over 60, the less likely you are to die.

So what is the major issue when you look at heart disease and heart attacks? Insulin resistance … The reason it’s being neglected is partly this flawed science on cholesterol. But also because there’s never been any effective drugs that target insulin resistance.

Therefore, because [there isn’t a] big market around something to sell, there aren’t many people that know about it. As you and I know, if you target insulin resistance through the right kind of diet and lifestyle changes, stress reduction, right kind of exercise, that’s going to have the biggest impacts on your health.”

Gauging Your Heart Disease Risk

Factors that can help gauge your heart disease risk include:

If you have 3 out of the following 5 indications of metabolic syndrome: insulin resistance, high triglycerides, low HDL, hypertension and increased waist circumference, then you are at high risk for heart disease. Another major risk factor for heart disease that receives virtually no attention is high iron levels.

In menstruating women, this is not an issue since they lose blood on a monthly basis. This is actually part of why premenopausal women have a decreased risk of heart disease.

In men, iron levels can rise to dangerously high levels. In my experience, the majority of adult males and postmenopausal women have elevated levels that put their health at risk. Checking your iron levels is easy and can be done with a simple blood test called a serum ferritin test.

I believe this is one of the most important tests that everyone should have done on a regular basis as part of a preventive, proactive health screen. If your levels are high, all you have to do is donate blood a few times a year.

The Connection Between Saturated Fats and Diabetes

Malhotra cites a 2014 Lancet study looking at the association between dietary saturated fat, plasma saturated fat and type 2 diabetes. Interestingly, while dietary saturated fats found in dairy products were strongly inversely associated with the development of type 2 diabetes (meaning it was protective), endogenously-synthesized plasma-saturated fat was strongly associated with an increased risk.

Endogenously-synthesized plasma-saturated fats are fatty acids produced by your liver in response to net carbohydrates, sugar and alcohol. These findings suggest eating full-fat dairy products may protect you against type 2 diabetes, whereas consuming too many net carbs (total carbs minus fiber) will increase your risk of type 2 diabetes — in part by raising the saturated fat levels in your bloodstream.

That said, I believe a caution may be warranted. Milk, even raw milk, is actually high in net carbs, which your body converts to glucose. So as a general rule, I recommend avoiding milk. Butter is an exception, as it’s almost pure fat and has virtually no net carbs.

Healthy Fat Tips

Here are a few tips to help ensure you’re eating the right fats for your health:

  • Use organic butter made from raw grass-fed milk instead of margarines and vegetable oil spreads.
  • Use coconut oil for cooking. It is primarily a saturated fat and more resistant to heat damage than other cooking oils. It will also help improve your ability to burn fat and serve as a great source of energy to help you make the transition to burning fat for fuel.
  • Sardines and anchovies are an excellent source of beneficial omega-3 fats and are also very low in toxins that are present in most other fish.
  • To round out your healthy fat intake, be sure to eat raw fats, such as those from avocados, raw dairy products, and olive oil, and also take a high-quality source of animal-based omega-3 fat, such as krill oil.

Why Statins Are a Bad Idea for Most People

In addition to the recommendation to follow a low-fat diet, many doctors are still avid prescribers of statins, which help lower your cholesterol. In fact, 1 in 4 Americans over the age of 40 are on these drugs; soon to be 1 in 3. Malhotra is greatly troubled by these kinds of statistics.

“This is a drug that was marketed over the last three decades as being a wonder drug. It’s driven a multi-trillion dollar industry. We’re only now realizing that the benefits of statins have been grossly exaggerated and the side effects underplayed. One of the reasons for that is that most if not all of the studies that drove the guidelines, and the information around statin prescription, were industry-sponsored studies.

One of the things we have neglected in medicine is this issue around absolute risk and relative risk. The reality is if you look at the published data … if you have heart disease and you’ve had a heart attack, then taking a statin every day for five years, there’s a 1 in 83 chance that [statin] will save your life.

That means in 82 of 83 cases, it’s not going to save your life. That information isn’t given to patients, but it’s really important. Actually that’s a much more informative and transparent way to understand the benefit they’re going to get.

On top of that when you look at people with lower risk, otherwise healthy people, there is no mortality benefit. People should know that if they haven’t had a heart attack, according to the published literature, they are not high risk and they’re going to live one day longer from taking statins.”

Statins Are Associated With Serious Side Effects

Then there’s the issue of side effects. According to Malhotra, between 1 in 3 and 1 in 5 patients suffer unacceptable side effects (which he qualifies as side effects that interfere with or diminish the quality of your life). Muscle pain is the most significant side effect reported followed by fatigue (mostly in women). This isn’t very surprising, considering the fact that statins are essentially a metabolic blocker and mitochondrial poison.

They inhibit an enzyme called HMG-CoA reductase. This is how they lower cholesterol. But that same enzyme is also responsible for a number of other things like making coenzyme Q10, which is why muscle pain and fatigue are so common. This is in fact a sign that your CoQ10 is being depleted, and you don’t have enough cellular energy.

Statins also block the formation of ketones, which are an essential part of mitochondrial nutrition and overall health. If you can’t make ketones, you impair the metabolism in your entire body, including your heart, thereby raising your risk for heart problems and a variety of other diseases. It’s also recently been established that within a few years of taking statins, the drug causes type 2 diabetes in one out of 100 patients.

That too can be a significant tradeoff that needs to be taken into account, as diabetes is a risk factor for heart disease and other chronic diseases. Dr. Michel De Lorgeril, a well-respected French cardiologist at Grenoble University recently reopened the debate about statins after publishing a review in which he questions whether statins actually have any benefit at all.

“He pointed out several discrepancies in the original trials … statistical manipulation, conflict of interest … ” Malhotra says. ”He’s actually suggested that maybe nobody benefits from statins; even people on statins for prevention.

He says that unless we get access to the raw data, independent analysis, the actual claims about the benefits of statins are not evidence-based. Now, I’m not personally saying that. I’m saying this is really intriguing and certainly raises as many questions … This is something that people need to know about. Even if we use the published literature at face value properly, people would be better informed. That’s the way forward in my view.”

More Information

Malhotra is currently finalizing a film called “The Big Fat Fix,” which will present a dietary protocol that incorporates many of the components of the Mediterranean lifestyle to help you reduce your risk of obesity, reverse type 2 diabetes and improve your cardiovascular health.

“We went to visit the village where Ancel Keys spent six months each year for 30 years doing his research. They had very high longevity. We try and find out what the secrets were and how things got misinterpreted,” Malhotra says. “This is really what the film will show. Where did things go wrong and where do we go from here?”

For more information, please visit Malhotra’s website, DoctorAseem.com, where you can find his blog, academic publications, newspaper articles and interviews.

from:     http://articles.mercola.com/sites/articles/archive/2016/06/05/saturated-fat-heart-disease-risk.aspx