Caffeine, Inflammation, & Longevity

Caffeine may counter age-related inflammation

A chronic inflammatory process that occurs in some, but not all, older people may trigger cardiovascular problems, a new Stanford study shows. Part of the solution might be found in a cup of coffee.

Jan 16 2017

Man standing in front of kids on a swing set

Mark Davis and his colleagues studied blood samples and a variety of data from more than 100 clinical trial participants and found a link between chronic inflammation and the chronic diseases that accompany aging.
Steve Fisch

Stanford University School of Medicine scientists have unearthed a connection between advancing age, systemic inflammation, cardiovascular disease and caffeine consumption.

Extensive analysis of blood samples, survey data and medical and family histories obtained from more than 100 human participants in a multiyear study has revealed a fundamental inflammatory mechanism associated with human aging and the chronic diseases that come with it.

The study, published online Jan. 16 in Nature Medicine, implicates this inflammatory process as a driver of cardiovascular disease and increased rates of mortality overall. Metabolites, or breakdown products, of nucleic acids — the molecules that serve as building blocks for our genes — circulating in the blood can trigger this inflammatory process, the study found.

The study also provides evidence that caffeine and its own metabolites may counter the action of these circulating nucleic-acid metabolites, possibly explaining why coffee drinkers tend to live longer than abstainers.

“More than 90 percent of all noncommunicable diseases of aging are associated with chronic inflammation,” said the study’s lead author, David Furman, PhD, a consulting associate professor at the Stanford Institute for Immunity, Transplantation and Infection. More than 1,000 papers have provided evidence that chronic inflammation contributes to many cancers, Alzheimer’s disease and other dementias, cardiovascular disease, osteoarthritis and even depression, he said.

“It’s also well-known that caffeine intake is associated with longevity,” Furman said. “Many studies have shown this association. We’ve found a possible reason for why this may be so.”

Mark Davis, PhD, a professor of microbiology and immunology and the director of the Stanford Institute for Immunity, Transplantation and Infection, shares senior authorship of the study with Benjamin Faustin, PhD, a cell biologist at the University of Bordeaux in France. Davis is also a Howard Hughes Medical Institute investigator.

Caffeine link

“Our findings show that an underlying inflammatory process, which is associated with aging, is not only driving cardiovascular disease but is, in turn, driven by molecular events that we may be able to target and combat,” said Davis, who holds the Burt and Marion Avery Family Professorship.

Notably, this inflammatory mechanism was found to be activated only in some, but not all, of the older study participants. Those in whom it was relatively quiescent tended to drink more caffeinated beverages. Laboratory experiments revealed that the mechanism was directly countered by caffeine and associated compounds.

Coffee cup in the midst of coffee beans

The researchers also found that the inflammatory mechanism was dampened among older participants who tended to drink more caffeinated beverages, such as coffee.
Marian Weyo/Shutterstock

The investigators made this discovery using data gathered from the Stanford-Ellison cohort, a long-term program begun 10 years ago by Davis and study co-author Cornelia Dekker, MD, professor of pediatric infectious diseases, to study the immunology of aging. In that program, healthy participants ages 20-30 and another group older than 60 were monitored annually via surveys, blood draws and reviews of their medical histories.

For the new study, the researchers compared blood drawn from older versus younger study participants to see which genes tended to be more highly activated in older people. They zeroed in on two clusters of genes whose activity was associated with the production of a potent circulating inflammatory protein called IL-1-beta. The genes within each cluster appeared to work in coordination with one another.

The researchers also looked at two particular groups of older participants: One with high activation of one or both inflammatory gene clusters, and the other with one or both clusters exhibiting low activation. On reviewing these individuals’ medical histories, the scientists learned that nine of the 12 subjects with high cluster activity had high blood pressure, compared with only one of the 11 subjects with low cluster activity. Follow-up studies by study co-author Francois Haddad, MD, a clinical associate professor of cardiovascular medicine, revealed that individuals in the “high” group were much more likely to have stiff arteries — a risk factor for cardiovascular complications — than those in the “low” group.

Furthermore, those in the low group were eight times as likely as those in the high group to report having at least one close family member who had lived to age 90 or older. Not only that, but participants in the high group who were older than 85 in 2008 were substantially more likely to have died by 2016 than were those in the low group. The high group’s blood also showed signs of increased activity of free radicals, which can harm cells, compared with the low group’s blood. The high group also had elevated concentrations of IL-1-beta, as well as of several nucleic-acid breakdown products that can be produced by free-radical action.

The researchers found that incubating a type of immune cell with two of those nucleic-acid metabolites boosted activity in one of the gene clusters, resulting in increased IL-1-beta production. When injected into mice, the substances triggered massive systemic inflammation, along with high blood pressure. In addition, immune cells infiltrated and clogged the animals’ kidneys, increasing renal pressure substantially.

How caffeine may affect longevity

Intrigued by the correlation between older participants’ health, gene-cluster activation and self-reported rates of caffeine consumption, the researchers followed up and verified that blood from the group with low cluster activity was enriched for caffeine and a number of its metabolites, compared with blood from the group with high cluster activity. (Examples of these metabolites are theophylline, also found in tea, and theobromine, which abounds in chocolate.)

Incubating immune cells with caffeine and its breakdown products along with the inflammation-triggering nucleic acid metabolites substantially prevented the latter from exerting their powerful inflammatory effect on the cells.

What we’ve shown is a correlation between caffeine consumption and longevity.

“That something many people drink — and actually like to drink — might have a direct benefit came as a surprise to us,” said Davis, who noted that the study did not prove a causal link. “We didn’t give some of the mice coffee and the others decaf. What we’ve shown is a correlation between caffeine consumption and longevity. And we’ve shown more rigorously, in laboratory tests, a very plausible mechanism for why this might be so.”

Other Stanford co-authors are postdoctoral scholars Junlei Chang, PhD, Christopher Bohlen, PhD, and Gabriela Fragiadakis, PhD; former graduate student Matthew Spitzer, PhD; life science research associate Edward Ganio; assistant professor of anesthesia, perioperative and pain medicine Brice Gaudilliere, MD, PhD; professor of microbiology and immunology Garry Nolan, PhD; and professor of hematology Calvin Kuo, MD, PhD.

Researchers from the Sidra Medical and Research Center in Qatar, the French National Institute of Health and Medical Research and the University of North Carolina also co-authored the study.

The study was funded by the National Institute of Allergy and Infectious Diseases (grant U19AI090019) and the Ellison Medical Foundation.

Stanford’s Department of Microbiology and Immunology also supported the work.

from:    https://med.stanford.edu/news/all-news/2017/01/caffeine-may-counter-age-related-inflammation-study-finds.html

Oh, Acupuncture!

Research Confirms this Holistic Treatment is Safer and More Effective than Morphine

Anna Hunt, Staff
Waking Times

A new study has discovered that acupuncture can be more effective in treating pain than intravenous morphine. In addition, the researchers discovered that acupuncture can work faster in relieving pain and have fewer adverse effects. The study was conducted over a one-year period at the Fattaouma Bourguiba University Hospital in Tunisia. The results were published in the American Journal of Emergency Medicine.

The Side Effects of Morphine Use

Morphine is an opioid pain medication which can have severe adverse effects. These include drowsiness, dizziness, constipation, stomach pain, nausea, vomiting, headache, tired feeling, anxiety and mild itching. Other risks associated with morphine use include misuse, abuse and addiction.

In addition, scientific research has shown that prescription opioids may actually worsen chronic pain. It appears that a holistic alternative to treating pain is much-needed in order to mitigate the dangers of conventional pharmaceutical pain treatment.

Now, a groundbreaking study shows that acupuncture is one of these effective holistic alternatives. Considering the study results, it may perhaps be even more effective than morphine.

Study: Acupuncture versus Morphine

A study performed in the Emergency Department of Fattouma Bourguiba University Hospital, which sees about 100,000 emergency patients per year, evaluated the pain treatment approach for 300 ED patients.

The research evaluated 300 emergency patients. 150 were administered up to 15 mg of morphine per day. The other 150 were given acupuncture treatment for address their pain. The researchers summarized the results as follows:

Success rate was significantly different between the 2 groups (92% in the acupuncture group vs 78% in the morphine group P < .001). Resolution time was 16 ± 8 minutes in the acupuncture group vs 28 ± 14 minutes in the morphine group (P < .005).

From the 5-minute time point, the acupuncture group reported significantly larger pain decrease compared with the morphine group.

Overall, 89 patients (29.6%) experienced minor adverse effects: 85 (56.6%) in morphine group and 4 (2.6%) in acupuncture group (P < .001). No major adverse effects were recorded during the study protocol.

In patients with acute pain presenting to the ED, acupuncture was associated with more effective and faster analgesia with better tolerance.

To paraphrase, the acupuncture group in the study experienced significant pain reduction, and the effect occurred faster and with fewer side effects when compared to the morphine group.

Western Medicine Recognizes Acupuncture as an Effective Medical Treatment

Acupuncture originated in China many centuries ago and soon spread to Japan, Korea and other parts of Asia as an accepted medical treatment. Throughout the Asian continent, it is widely used in health care systems, officially recognized by governments, and well received by the general public.

In 1996, acupuncture became an accepted form of medical treatment endorsed by the World Health Organization (WHO). The WHO based their endorsement on data from numerous controlled clinical trials conducted over the two previous decades. The WHO report that resulted from the analysis of these clinical trials states:

Diseases, symptoms or conditions for which acupuncture has been proved – through controlled trials – to be an effective treatment:

  • Adverse reactions to radiotherapy and/or chemotherapy

  • Allergic rhinitis (including hay fever)

  • Biliary colic

  • Depression (including depressive neurosis and depression following

  • stroke)

  • Dysentery, acute bacillary

  • Dysmenorrhoea, primary

  • Epigastralgia, acute (in peptic ulcer, acute and chronic gastritis, and gastrospasm)

  • Facial pain (including craniomandibular disorders)

  • Headache

  • Hypertension, essential

  • Hypotension, primary

  • Induction of labour

  • Knee pain

  • Leukopenia

  • Low back pain

  • Malposition of fetus, correction of

  • Morning sickness

  • Nausea and vomiting

  • Neck pain

  • Pain in dentistry (including dental pain and temporomandibular

  • dysfunction)

  • Periarthritis of shoulder

  • Postoperative pain

  • Renal colic

  • Rheumatoid arthritis

  • Sciatica

  • Sprain

  • Stroke

  • Tennis elbow

Notice the multiple mentions of conditions that involve pain, such as low back pain, neck pain and headaches. In their report, the WHO also stated that acupuncture has shown to have a therapeutic effect on abdominal pain, cancer pain, facial spasms, and labour pain (although the organization did not have sufficient clinical data to include these in the effective treatment list above.)

Undoubtedly, acupuncture can play a powerful role in pain management. It is an effective drug-free alternative to reducing pain with very few side effects that has been proven over the ages. Finally, science is catching up to reinforce this claim.

from:     http://www.wakingtimes.com/2017/01/12/research-confims-holistic-treatment-more-effective-morphine/

Considering Acupuncture

Acupuncture: Why It Works

 By Dr. Mercola

More than 3 million Americans receive acupuncture each year, and its use is increasing.1 While there are a variety of acupuncture techniques, those typically used in the U.S. incorporate traditions from China, Japan and Korea and involve penetrating your skin with a thin needle at certain points on your body.

The needle is then stimulated by hand or electrically.2 Acupuncture has been in use for thousands of years around the globe, and it has withstood the test of time because it works to safely relieve many common health complaints.

How it works has remained largely a mystery, but last year researchers revealed a biochemical reaction that may be responsible for some of acupuncture’s beneficial effects.

Scientists Reveal How Acupuncture Reduces Inflammation and Pain

An animal study looking into the effects of acupuncture on muscle inflammation revealed that manual acupuncture downregulates (or turns off) pro-inflammatory cells known as M1 macrophages. At the same time, it upregulates (or activates) anti-inflammatory M2 macrophages, thereby reducing pain and swelling.3

This is an effective strategy because M2 macrophages are a source of anti-inflammatory interleukin-10 (IL-10), a cytokine involved in immune response. It’s thought that upregulating M2 macrophages leads to an increase in IL-10, which subsequently helps relieve pain and inflammation. The Epoch Times reported:4

Acupuncture literally flips a switch wherein initial inflammatory responses are reduced and the secondary healing responses are promoted.

M1 macrophage downregulation and M2 macrophage upregulation triggered by acupuncture was positively associated with reductions in muscle pain and inflammation.”

It’s likely that acupuncture works via a variety of mechanisms. In 2010, for instance, it was found that acupuncture activates pain-suppressing receptors and increased the concentration of the neurotransmitter adenosine in local tissues.5

Adenosine slows down your brain’s activity and induces sleepiness. According to a Nature Neuroscience press release:6

“ … [T]he authors propose a model whereby the minor tissue injury caused by rotated needles triggers adenosine release, which, if close enough to pain-transmitting nerves, can lead to the suppression of local pain.”

Acupuncture Influences Your Body on Multiple Levels

With documented use dating back more than 2,500 years, acupuncture is based on the premise that there are more than 2,000 acupuncture points in the human body, which are connected by bioenergetic pathways known as meridians.

According to traditional medicine, it is through these pathways that Qi, or energy, flows, and when the pathway is blocked the disruptions can lead to imbalances and chronic disease.

Acupuncture is proven to impact a number of chronic health conditions, and it may work, in part, by stimulating your central nervous system to release natural chemicals that alter bodily systems, pain and other biological processes. Evidence suggests that acupuncture may also work by:7

  • Stimulating the conduction of electromagnetic signals, which may release immune system cells or pain-killing chemicals
  • Activation of your body’s natural opioid system, which may help reduce pain or induce sleep
  • Stimulation of your hypothalamus and pituitary gland, which impact numerous body systems
  • Change in the secretion of neurotransmitters and neurohormones, which may positively influence brain chemistry

Acupuncture May Relieve Pain From Knee Osteoarthritis

Acupuncture is often used for the treatment of chronic pain, and it may be particularly useful for pain from knee osteoarthritis.

In a study by researchers from the Chengdu University of Traditional Chinese Medicine, acupuncture received five times a week for four weeks significantly reduced pain and improved stiffness in patients with knee osteoarthritis.8

In this study, the improvements increased even more when acupuncture was combined with Chinese massage called Tui Na. Other research has also shown benefits, including one of the longest and largest studies on the topic to date.

More than 550 patients diagnosed with knee osteoarthritis took part in the 26-week trial. The participants were randomly assigned to receive one of three treatments: acupuncture, sham acupuncture, or self-help strategies recommended by the Arthritis Foundation (the latter served as a control group).

Significant differences in response were seen by week eight and 14, and at the end of the trial, the group receiving real acupuncture had a 40 percent decrease in pain and a nearly 40 percent improvement in function compared to baseline assessments — a 33 percent difference in improvement over the sham group.9

Acupuncture for Relief of High Blood Pressure

There is some evidence that acupuncture may help lower high blood pressure while also relieving associated anxiety, headaches, dizziness, palpitations and tinnitus.

It’s known that high blood pressure leads to elevated concentrations of inflammation-causing tumor necrosis factor alpha (TNF-α) and TNF-α-stimulated endothelin (ET), peptides involved in constricting blood vessels and raising blood pressure.10,11

It’s thought that acupuncture may downregulate TNF-α and ET, thereby reducing blood pressure. In another study of patients with high blood pressure, 30 minutes of electroacupuncture (in which the needles are stimulated with electricity) a week led to slight declines in blood pressure.12

Study co-author Dr. John Longhurst, a cardiologist at the University of California, Irvine, told WebMD, “Potentially, blood pressure can be kept low with a monthly follow-up treatment.” He continued:13

“A noticeable drop in blood pressure was observed in 70 percent of the patients treated at the effective points, an average of 6 to 8 mm Hg for systolic blood pressure [the top number] and 4 mm Hg for diastolic blood pressure [the lower number].”

Acupuncture Even Works for Fibromyalgia Pain and Pain in Children

One of the most common uses for acupuncture is in treating chronic pain. One analysis of the most robust studies available concluded that acupuncture has a clear effect in reducing chronic pain, more so than standard pain treatment.14

Study participants receiving acupuncture reported an average 50 percent reduction in pain, compared to a 28 percent pain reduction for standard pain treatment without acupuncture.

Even fibromyalgia pain, which can be difficult to treat and is associated with sleep problems, fatigue and depression, may be improved.

In one study, 10 weeks of acupuncture decreased pain scores in fibromyalgia patients by an average of 41 percent, compared with 27 percent in those who received a sham procedure.15

The pain relief lasted for at least 1 year, leading researchers to conclude, “ … [T]he use of individualized acupuncture in patients with fibromyalgia is recommended.” Acupuncture also appears to be a safe and effective treatment for relieving chronic pain in children.

In a study of 55 children with chronic pain, those who received eight acupuncture sessions (each lasting about 30 minutes) reported significant reductions in pain and improved quality of life.16

Acupuncture for Depression, Cancer Patients and More

Acupuncture’s benefits extend to a myriad of other health conditions as well. Research suggests acupuncture works as well as counseling for treating depression, for instance.17 It may also improve fatigue, anxiety and depression in cancer patients in as little as eight weeks — and much more.18

The World Health Organization (WHO) conducted an extensive review and analysis of clinical trials related to acupuncture and reported the procedure has been proven effective for the following diseases:19

Adverse reactions to radiotherapy and/or chemotherapy Allergic rhinitis (including hay fever) Biliary colic
Depression (including depressive neurosis and depression following stroke)  Acute bacillary dysentery Primary dysmenorrhea
Acute epigastralgia (in peptic ulcer, acute and chronic gastritis, and gastrospasm) Facial pain (including craniomandibular disorders) Headache
Essential hypertension Primary hypotension Induction of labor
Knee pain Leukopenia Low back pain
Correction of malposition of fetus Morning sickness Nausea and vomiting
Neck pain Pain in dentistry (including dental pain and temporomandibular dysfunction) Periarthritis of shoulder
Postoperative pain Renal colic Rheumatoid arthritis
Sciatica Sprain Stroke
Tennis elbow

Additionally, acupuncture has also shown a therapeutic effect for treating the following diseases and conditions, which range from premenstrual syndrome (PMS) and addictions to whooping cough, although further research is needed:

Abdominal pain (in acute gastroenteritis or due to gastrointestinal spasm) Acne vulgaris Alcohol dependence and detoxification Bell’s palsy
Bronchial asthma Cancer pain Cardiac neurosis Chronic cholecystitis, with acute exacerbation
Cholelithiasis Competition stress syndrome Closed craniocerebral injury Non-insulin-dependent  diabetes mellitus
Earache Epidemic hemorrhagic fever Simple epistaxis  (without generalized or local disease) Eye pain due to subconjunctival injection
Female infertility Facial spasm Female urethral syndrome Fibromyalgia and fasciitis
Gastrokinetic disturbance Gouty arthritis Hepatitis B virus carrier status Herpes zoster (human (alpha) herpesvirus 3)
Hyperlipaemia Hypo-ovarianism Insomnia Labor pain
Lactation deficiency Male sexual dysfunction, non-organic Ménière disease Postherpetic neuralgia
Neurodermatitis Obesity Opium, cocaine and heroin dependence Osteoarthritis
Pain due to endoscopic examination Pain in thromboangiitis obliterans Polycystic ovary syndrome (Stein-Leventhal syndrome) Postextubation in children
Postoperative convalescence Premenstrual syndrome Chronic prostatitis Pruritus
Radicular and pseudoradicular pain syndrome Primary Raynaud syndrome Recurrent lower urinary tract infection Reflex sympathetic dystrophy
Traumatic retention of urine Schizophrenia Drug-induced Sialism Sjögren syndrome
Sore throat (including tonsillitis) Acute spine pain Stiff neck Temporomandibular joint dysfunction
Tietze syndrome Tobacco dependence Tourette syndrome Chronic ulcerative colitis
Urolithiasis Vascular dementia Whooping cough (pertussis)

Are Certain Types of Acupuncture Better Than Others?

Similar benefits have been found for different types of acupuncture treatment. For instance, sometimes the stimulation of acupuncture points is done using electricity, lasers or acupressure (the use of pressure to stimulate acupuncture points).

The term acupuncture is often used to describe all of these modalities, as each has shown similar benefits. This means that if you like the idea of trying a natural, ancient technique like acupuncture, but don’t like the idea of having needles inserted into your body, there are needle-free alternatives, such as the Emotional Freedom Techniques, or EFT, you can try that may offer many of the same benefits.

If you decide to try out traditional acupuncture, be aware that the success of your treatment depends on the expertise of your practitioner. While there are acupuncturists that have general specialties, there are also those that specialize in different health conditions, such as pain relief, depression, infertility or neurological disorders. Choose an acupuncturist that is experienced in your area of need who will work with you to develop a plan for healing.

from:    http://articles.mercola.com/sites/articles/archive/2016/06/23/how-does-acupuncture-work.aspx

Benefits of Cannabidiol

Cannabidiol (CBD): The Cat’s Out of the Bag with This Cure-All

Makia Freeman
Contributor, ZenGardner.com

The truth about Cannabidiol (CBD)

and the cannabis plant in general can no longer be suppressed – and the exciting thing is that we are just at the beginning. We are literally just at the start on the long road of cannabis knowledge, which will take us to a deeper understanding of this astonishing plant, its varied uses and its manifold medical benefits. We still don’t even know how many cannabinoids (natural chemical compounds endemic to the cannabis plant) it contains – over the years the number has been revised in various places from 66 to 85 to 113+. We certainly don’t know the full range of effects of these cannabinoids, nor do we understand the synergistic way they work together, which is of the utmost importance. However, we do know enough to say that one of the foremost cannabinoids is cannabidiol or CBD, and we do know that it has incredible potential for healing a wide range of diseases, including diabetes, insomnia, anxiety, depression, migraines, asthma, scar tissue, Crohn’s, epilepsy, seizures, schizophrenia, Alzheimer’s, Parkinson’s and cancer. Ironically, the whole propaganda campaign of “reefer madness” that tried to demonize marijuana in the 1930s-1950s insinuated that pot caused schizophrenia, and while THC can have some mildly negative psychoactive effects when smoked, it may turn out that CBD-rich cannabis oil cures schizophrenia, not causes it. This demonization campaign, as usual, was led by the Rockefellers and other rich NWO families who were scared that cannabis would destroy their monopolies, such as the Western medical drug industry.

Clearly, the tides of cannabis perception are turning, and many people have overcome the stigma to explore the vast nutritional and medicinal benefits of cannabis. This article focuses on the healing potential of the preeminent cannabinoid, CBD.

Guess Where Else Cannabinoids are Found?

Before we break down the phenomenal effects of CBD, here is a mind-blowing fact. Cannabinoids aren’t just found in the cannabis plant. They’re also found somewhere closer to home: you! That’s right: the human body itself has an entire system which utilizes cannabinoids. It is known as the endocannabinoid system (“endo” is from a Greek word meaning “within”). In this way, we can distinguish among endocannabinoids (those produced by the human body), phytocannabinoids (those produced by the cannabis plant) and synthetic cannabinoids (the approximately 17 synthetic versions produced by the pharmaceutical cartel). Synthetic cannabinoids, by the way, are Big Pharma’s way of trying to pirate and cash in on Nature by modifying or isolating a natural chemical or compound, making it slightly different to its natural state, getting a patent, then marketing it as a drug with a governmentally enforced monopoly. Some synthetic cannabinoids (such as K2, spice, marinol, etc.) have been taken off the market due to their dangerous nature, but after all, they are part of the Big Pharma business plan, and the greater New World Order synthetic agenda, so what do you expect?

cannabidiol CBD cannabis plant

The Endocannabinoid System

The cannabinoid receptors (CB1, CB2, etc.), endocannabinoids and the related enzymes all make up the endocannabinoid system – and it’s not just some insignificant little system in the body. Evidence shows it to be essential in most if not all physiological systems, responsible for numerous processes including appetite, pain-sensation, mood, memory and immunity (yes, the endocannabinoid system influences the immune system too). The Italian researcher, Vincenzo Di Marzo, summed it up well in his 1998 study Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action:

“‘Relax, eat, sleep, forget and protect’ might be some of the messages that are produced by the actions of endocannabinoids, alone or in combination with other mediators …”

cannabidiol CBD chemical formula

How CBD Works

CBD is a miracle compound. Unlike THC, it does not bind to the body’s cannabinoid receptors (CB1 or CB2), so it is not psychoactive and does not produce the high effect. Cannabidiol works through a number of complex mechanisms. Preclinical studies indicate that cannabidiol has the following list of extensive healing properties. The first 5 items on the list below all pertain to cannabidiol’s capacity as an anti-carcinogenic agent:

Anti-Proliferative: CBD stops cancer cells proliferating or reproducing. Many of its effects listed below stem from its ability to activate PPAR receptors. As the article How CBD Works states, “CBD also exerts an anti-cancer effect by activating PPARs [peroxisome proliferator activated receptors] that are situated on the surface of the cell’s nucleus. Activation of the receptor known as PPAR-gamma has an anti-proliferative effect as well as an ability to induce tumor regression in human lung cancer cell lines.”

Anti-Angiogenic: As the quote above also reveals, cannabidiol can stop cancer cells in another way, by preventing malignant tumors from forming the blood vessels they need to grow. The process of blood vessel creation is called angiogenesis, and since cannabidiol halts this, it is deemed anti-angiogenic.

Anti-Mitogenic: There is a 3rd way cannabidiol prevents cancer. It hinders or stops cell division (mitogenesis). One of the hallmarks of cancer is its unbridled growth, and amazingly, CBD actually stops the cancer spreading out of control by preventing the cancer cell from dividing and reproducing, and thus is deemed anti-mitogenic.

Anti-Metastatic: Metastasis is the process by which a cancer can spread around the body, especially to other organs which have no direct contact with it. Cannabidiol prevents cancer from spreading to other organs, so it is called anti-metastatic.

Pro-Apoptotic: Apoptosis is the medical word for programmed cell death. It’s an important part of every healthy and functional cell that it contains a program for apoptosis, so it can commit suicide or let itself die if it is compromised. Cancer cells characteristically do not undergo apoptosis, however cannabidiol is pro-apoptotic and actually induces cancer cells to die. Incredible!

Anti-Psychotic: In addition to showing impressive potential for curing cancer, cannabidiol also exhibits anti-psychotic properties, which means it could help heal a whole host of mental illnesses. As the aforementioned article How CBD Works states: “CBD’s enzyme-mediated activation of the PPAR-alpha receptor may have antipsychotic effects. Polymorphisms or mutations in the gene encoding PPAR-alpha can result in deficient PPAR-alpha signaling, which has been linked to schizophrenia. PPAR-alpha activation is both anti-inflammatory and can decrease dopamine release, thereby minimizing schizophrenic symptoms.”

Neuro-Protective: Neurodegenerative diseases (such as Alzheimer’s and Parkinson’s) are another set of horrible diseases which are claiming the lives or more and more people. Fortunately, CBD shows potential for healing these too. Again, the issue comes back to the PPAR-activation (same article): “PPAR-gamma activation degrades amyloid-beta plaque, a key molecule linked to the development of Alzheimer’s disease. This is one of the reasons why cannabidiol, a PPAR-gamma agonist, may be a useful remedy for Alzheimer’s patients. As an aside, PPAR receptors also regulate genes that are involved in energy homeostasis, lipid uptake, insulin sensitivity, and other metabolic functions. Diabetics, accordingly, may benefit from a CBD-rich treatment regimen.”

Anti-Inflammatory: Inflammatory diseases are another massive set of diseases that haunt the populations in developed countries, especially the US. Many nutritional experts and doctors have highlighted the strong connection between inflammation and disease. As Dr. Mark Hyman writes:

“Inflammation is a “hot” topic in medicine. It appears connected to almost every known chronic disease — from heart disease to cancer, diabetes to obesity, autism to dementia, and even depression. Other inflammatory diseases such as allergies, asthma, arthritis, and autoimmune disease are increasing at dramatic rates …”

According to various studies cited by Medical Marijuana Inc, cannabidiol stops inflammation in various ways:

“[cannabidiol decreases] the production and release of pro-inflammatory cytokines and decrease the activation of the LPS-induced STAT1 transcription factor, a key factor in some of the pro-inflammatory process. CBD, however, also reduces the activity of the NF-kappaB pathway, a primary pathway regulating pro-inflammatory genes, and upregulates the activation of the STAT3 transcription factor, which induces anti-inflammatory events (Kozela, et al., 2010).”

Analgesic: Analgesic means pain-relieving. CBD is analgesic and is thus indicated for those suffering from inflammatory disease or conditions with chronic pain.

Anti-Convulsant: CBD has become famous for its ability to stop seizures and treat diseases such as epilepsy. The overwhelming consensus of case studies, surveys and pre-clinical animal studies shows that cannabidiol is a powerful anti-convulsant. For a sampling of the studies done on this, see here and here.

Pro-Anxiolytic: Finally, CBD also helps calms the nerves and reduce or eliminate anxiety, and thus is anti-anxiety or medically speaking pro-anxiolytic. The reason why CBD has this effect is probably due to its activation of the adenosine receptor. Adenosine receptors play major roles in brain and cardiovascular function (regulating oxygen intake and blood flow), as well as having anti-inflammatory effects throughout the body, which ties in with CBD’s anti-inflammatory properties.

cannabidiol CBD cannabis plant closeup

How Cannabis Kills Cancer Cells

For those wanting a little more information on how cannabis kills cancer cells, I recommend watching a few of these short videos. The 1st video shows how and why cannabis curse cancer. The 2nd video is an interview with a man called Dennis Hill, a survivor of stage IV prostate cancer. Dennis reveals how our bodies make cancer cells all the time, but our immune system (which includes the endocannabinoid system) can normally handle them. However, when the immune system is compromised, it gets behind on killing cancer cells.

Cancer cells have distorted or damaged DNA. Luckily, when a cell turns cancerous, the number of cannabinoid receptors in the cell increases. The body uses its endocannabinoid anandamide to stimulate the production of ceramide, which kills cancer cell mitochondria, starving the cancer cell. The ceramide is intelligently guided; it somehow “knows” to kill damaged cells only and leave the healthy ones intact, much like the way vitamin B17, amygdala or laetrile works to selectively target cancer cells too.

The Future of CBD Oil: Made Without Solvents

Rick Simpson, the Canadian hero who made CBD-rich cannabis oil, gave it away for free and healed many people, came up with a form of CBD oil where he used a solvent to extract it. However, there are now many companies who are producing high-quality CBD oil from non-GMO, non-pesticided hemp, which they then decarboxylate (turn the acidic forms of the cannabinoids into the non-acidic forms, i.e. turn CBDa into CBD and THCa into THC, etc.). I believe in the future, due to the unstoppable momentum of cannabis oil, medical marijuana will become completely decriminalized and legalized, and people all over will have access to high therapeutic grade CBD oil which contains no THC or psychoactive agents.

Conclusion: Let’s Explore the Many Uses of Cannabis and CBD Oil

There are no coincidences in our world – only magic, mystery, synchronicity, conspiracy and connection of which we are often unaware. The sheer fact that our body has its own endocannabinoid system, parallel to the phytocannabinoid system of the cannabis plant, is a fact of key significance and beyond mere coincidence. Call it what you want – cannabis, hemp, marijuana, pot, weed, ganja or kush – this plant has massive potential as a first-class healer extraordinaire. It’s time for all of us around the world to study and use this plant for the bounty of benefits it offers, including making paper, textiles, cloth, rope, oil and fuel, as well as for its nutritional benefits (hemp seed, hemp seed oil) and medical benefits (CBD oil). It has already saved people’s lives. Imagine what else it can do …

from:    http://www.zengardner.com/cannabidiol-cbd-cats-bag-cure/

Dealing with Inflammation

Which Foods Should You Cut to Fight Inflammation?

foods inflammationNobody ever really looks into solutions and therapies for inflammation until it comes time to deal with it. If you’ve ever suffered from inflammation or the number of diseases that stem from it, such as arthritis and other chronic diseases, you’ve probably asked what solutions there are to help relieve the pain.

What you should be asking is how you can prevent inflammation in the first place.

Inflammation is a natural product of the body to repair tissue injury, chronic inflammation is when that process gets out of hand and can’t stop. This overreaction is brought on by certain foods that you consume every day, but luckily they are easily removable!

So what foods should you avoid?

Here is a list of the 3 major chronic inflammation causes:

1. Anything That can Trigger an Allergy

If you have any sort of allergy, you know that it sets your body off in the wrong way. But who knew this could also affect your body’s inflammation processes in the wrong way? It’s important to make sure that you are not eating anything that your body can’t handle, even if it is only a mild reaction.

Common allergens like eggs, dairy products and vegetables are the hardest to avoid since they can be found in some foods that you wouldn’t expect. Make sure you check the ingredients of the food you eat for any form of what you’re allergic to! You might be surprised that something you love actually contains that pesky allergen!

2. Fried Foods

You probably already know that deep fried foods are bad for you for other reasons, but they actually do their part in promoting inflammation as well.

It’s in the oil. Most oils used in fried foods are already stripped of their natural nutrients, and whatever might be left over is destroyed in the heat needed to fry the food. What is left is a kind of toxin that overloads the elimination system of the body and causes the inflammation process to go crazy.

3. Processed Foods and Drinks

Just like the oil in fried foods, most things that are processed before being sold in supermarkets end up losing the majority of their nutrients. Pastries, processed soups, fizzy drinks, all of these and more have been altered so that they do more bad to our bodies than good.

Cutting these foods out of your diet will help your inflammation system do only what is necessary to repair your tissue and nothing else. No overtime, no chronic inflammation, no arthritis.

And don’t you worry, there are other solutions as well!

If you already find yourself with chronic inflammation there are many natural foods that contain anti-inflammatory properties that are readily available at the supermarket such as:

-Coconut oil: the nutrients in coconut oil are not destroyed when cooked, and are easily digested.

-Fish: contains natural anti-inflammatory properties and is known to encourage the production of pain relieving hormones in the body.

-Ginger: Contains significant anti-inflammatory properties in the root.

-Cayenne peppers: contains capsaicin, an anti-inflammatory agent.

from:    http://www.realfarmacy.com/inflammation-foods/

The Benefits of Stinging Nettles

 Healing Allergy Inflammation With Stinging Nettle

Many of us look forward to Spring. The weather warms up.  We start spending more time outdoors. Plants are growing, and flowers are blooming everywhere. When spring is in the air, so is pollen. For those of us with seasonal allergies, spring is not as lovely. Fortunately, nature has a way with timing and can really help us out if we pay attention.

In the spring, just as all those flowers, grasses and trees are blooming and releasing clouds of pollen, stinging nettles (Urtica dioica) are popping up in full force, ready to come to the rescue.  Not only are they an amazing superfood and an all around useful medicinal plant, nettles work wonders for reducing inflammation.

This is an important thing to know because inflammation doesn’t stop with our sinuses and seasonal respiratory allergies. Food allergies and associated digestive inflammation are a huge problem for many people, and most of the over-the-counter treatments only make the situation worse.

Nettles are a safe, soothing treatment for inflammation, offering the added benefits of vitamins, minerals, and immune-boosting properties.  It’s time to make friends with the stinging nettle, folks. You won’t regret it.

Nettles and Seasonal Allergies

Stinging nettles have been used for centuries as a natural treatment for seasonal allergies,  hay fever, asthma, and hives. Research has shown that consuming nettles in freeze dried capsules effectively reduces histamine levels in the body, thus reducing inflammation of affected tissues. Even a simple nettle tea consumed daily throughout the pollen and allergy season will alleviate allergy symptoms.

Common symptoms such as itchy eyes, sneezing, runny noses, and stuffed up sinuses  are treated as effectively, if not more so, by stinging nettle than over the counter allergy medications. It has been suggested that nettles actually desensitize the body to allergens and decrease our reaction to the allergens over time. Nettles will also spare you the side effects that come with allergy medications, like drowsiness or irritation and ulcers of the digestive tract, which leads to a whole other set of inflammation issues you don’t want.

With high levels of iron, calcium, potassium, phosphorous, sulphur, chromium, cobalt, magnesium, silicon, zinc, vitamin C, vitamin A, vitamin K,  iron, and chlorophyll,  they will leave you feeling energized while assisting your immune system in overcoming the allergy response.

Nettles and Digestive Inflammation

Inflammation of the digestive tract has become a common reality that many of us deal with, and this isn’t really surprising when you look at the variety of culprits  and how common they are in our modern lives.  Food allergies, Candida imbalance, NSAID medications (ibuprofin, aspirin, etc.), chronic stress, sugars, highly processed foods, and environmental toxins are all potential sources of digestive inflammation and daily struggles for a lot of folks out there.

The most common go-to treatment tends to be over-the-counter NSAID medications that target pain and swelling, but they, in fact, contribute to the irritation and inflammation of the digestive tract, creating a vicious cycle that is difficult to break. Here is where the anti-inflammatory benefits of nettles come into play.

When the leaves and stems of stinging nettle are digested, either in the form of a tea, tincture, capsule, or culinary green, the chemical constituents interfere with the body’s production of prostaglandins, resulting in an anti-inflammatory response. Nettles also interfere with pain signals in the body, clean out the intestinal tract, and boost the immune system, providing relief and healing for issues of the digestive system.

Given these healing properties, nettles are beneficial in healing leaky gut syndrome and are listed as a therapeutic ingredient in the GAPS (Gut and Psychology Syndrome) diet. Nettle tea has been noted as a successful treatment for individuals dealing with gluten intolerance and Celiac disease to reduce gastrointestinal inflammation and discomfort.

Ulcerative colitis and ulcers in other areas of the digestive tract can also benefit from nettles, as they stop internal bleeding  and re-build  the blood with their high iron content and aided absorption.

Nettles for Pet Allergy Care

Allergies are not only an issue for people; their canine companions suffer from them as well. Dog owners may associate the springtime with treating “itchy dog syndrome” along with their pet’s eye discharge, ear infections, and overall discomfort. Stinging nettle is a natural anti-inflammatory for dogs to reduce levels of histamines, detox their system, and help desensitize their body to allergens. By giving dogs regular nettle supplements during allergy season, their allergies have been shown to actually go away over time. Nettles can be administered to dogs by adding it in freeze dried form to their food or through supplementation.

Where to Find Nettles

If you are interested in wildcrafting your own nettles, you can find them growing in moist soils at the edge of forests, streams, marshy areas, and pastures. You may even find them growing in your own backyard. They are one of the first plants to come up in the spring. They are very distinct with square shaped stems and opposite, serrated leaves tapered to a point, so they are fairly easy to find. With a good plant ID guide and advice from local foragers, you can venture out and gather your own nettles all through the spring months.

You can also establish a nettle patch at home in your garden either with nettle seeds from an heirloom seed company or by transplanting rhizomes from wild nettle patches. If you are working with fresh nettles, be sure to wear gloves while picking and handling them in the kitchen. The prickly hairs on the skin contain formic acid and can cause an irritation to the skin, which is a nuisance but not harmful. Cooking, drying, and grinding will break down the hairs so they are no longer an issue.

Nettles are very easy to dry and use throughout the rest of the year when they aren’t found growing outside. For those of us who may not have access to foraging areas or garden space, you can always purchase dried nettle leaf and a variety of nettle supplements. Sometimes grocery stores will even carry fresh wildcrafted nettles in the spring.

Anti-Inflammatory Nettle Tea Recipe

  • 3 fresh nettle tops (three leaf nodes down the plant) or 3 Tbsp dried nettle leaf
  • 1 Tbsp dried marshmallow root
  • 2 slices fresh ginger root

Boil 4 cups water, and pour over herbs. Steep for 7 minutes, covered. I prefer using a quart mason jar with a lid.

Hay Fever Relief Nettle Tea Recipe

  • 3 fresh nettle tops (three leaf nodes down the plant) or 3 Tbsp dried nettle leaf
  • 1 Tbsp dried elder flower
  • 1 Tbsp dried chamomile

Boil 4 cups water, and pour over herbs. Steep for 7 minutes covered. I prefer using a quart mason jar with a lid.

 

from:    http://www.organiclifestylemagazine.com/healing-allergy-inflammation-with-stinging-nettle

Inflammation & Heart Disease

Prestigious Heart Surgeon’s Confession Reveals the Truth About Heart Disease

Statin DrugsAlex Pietrowski, Staff

Waking Times

A physician’s word is often taken very seriously and with little skepticism. An opinion from one or two doctors, when made in a professional office or hospital, can persuade a worried patient to take drugs with complex side-effects, or even undergo traumatic treatments such as radiation and chemotherapy. Yet, when the same doctors, with years of experience and thousands of satisfied customers, give an opinion that questions a therapy established by mainstream medicine, the mainstream media calls them irresponsible, or quacks, or even criminals.

Many doctors are highly admirable people, bu they are still human beings. They all make mistakes, they all learn from them, but the really good ones are willing to admit to them.

Dr. Dwight Lundell

Which brings us to Dr. Dwight Lundell. He’s an experienced heart surgeon and retired Chief of Staff and Chief of Surgery at Banner Heart Hospital in Mesa, Arizona. Not so long ago, Dr. Lundell made the following statement of confession:

“We physicians with all our training, knowledge and authority often acquire a rather large ego that tends to make it difficult to admit we are wrong. So, here it is. I freely admit to being wrong. As a heart surgeon with 25 years experience, having performed over 5,000 open-heart surgeries, today is my day to right the wrong with medical and scientific fact.

I trained for many years with other prominent physicians labeled “opinion makers.” Bombarded with scientific literature, continually attending education seminars, we opinion makers insisted heart disease resulted from the simple fact of elevated blood cholesterol. The only accepted therapy was prescribing medications to lower cholesterol and a diet that severely restricted fat intake. The latter of course we insisted would lower cholesterol and heart disease. Deviations from these recommendations were considered heresy and could quite possibly result in malpractice. It Is Not Working!

These recommendations are no longer scientifically or morally defensible.”

Not surprisingly, Lundell’s statement regarding the medical establishment’s approach to treating heart disease caused a ripple in the medical industry. It challenged the validity of statins – commonly known as cholesterol-lowering medications – such as Lipitor, Crestor, Zocor, and others.

The reason Lundell’s statement created such a buzz is because statins are big business. In the United States alone, about 25% of the population takes statin medications. They cost from as little as $53 per month to more than $600. Pfizer’s Lipitor went on sale in 1997 and its lifetime sales have surpassed $125 billion. AstraZeneca’s Crestor was the top-selling statin in 2013, generating $5.2 billion in revenue that year alone. The statin industry is estimated at around $30 billion in sales per year. Nevertheless, in the United States, more die each year of heart disease than ever before.

Lundell went on to say:

“The discovery a few years ago that inflammation in the artery wall is the real cause of heart disease is slowly leading to a paradigm shift in how heart disease and other chronic ailments will be treated. The long-established dietary recommendations have created epidemics of obesity and diabetes, the consequences of which dwarf any historical plague in terms of mortality, human suffering and dire economic consequences.

I have peered inside thousands upon thousands of arteries. A diseased artery looks as if someone took a brush and scrubbed repeatedly against its wall. Several times a day, every day, the foods we eat create small injuries compounding into more injuries, causing the body to respond continuously and appropriately with inflammation. While we savor the tantalizing taste of a sweet roll, our bodies respond alarmingly as if a foreign invader arrived declaring war. Foods loaded with sugars and simple carbohydrates, or processed with omega-6 oils for long shelf life have been the mainstay of the American diet for six decades. These foods have been slowly poisoning everyone.”

Simply, it is the foods that are baked or soaked in soybean oil and ones that are processed for long shelf-life that are creating an extreme imbalance of omega-6 and omega-3 fats in people’s bodies. Lundell estimates the ratio of imbalance “ranges from 15:1 to as high as 30:1 in favor of omega-6.” A healthy ratio is closer to 3:1.

But what makes Lundell’s statements controversial is that cholesterol does not cause heart disease…which makes statin drugs superfluous. And he suggests a treatment to heart disease that doesn’t make Big Pharma any money:

“Simply stated, without inflammation being present in the body, there is no way that cholesterol would accumulate in the wall of the blood vessel and cause heart disease and strokes. Without inflammation, cholesterol would move freely throughout the body as nature intended. It is inflammation that causes cholesterol to become trapped.

Since we now know that cholesterol is not the cause of heart disease, the concern about saturated fat is even more absurd today. The cholesterol theory led to the no-fat, low-fat recommendations that in turn created the very foods now causing an epidemic of inflammation. Mainstream medicine made a terrible mistake when it advised people to avoid saturated fat in favor of foods high in omega-6 fats. We now have an epidemic of arterial inflammation leading to heart disease and other silent killers. What you can do is choose whole foods your grandmother served and not those your mom turned to as grocery store aisles filled with manufactured foods. By eliminating inflammatory foods and adding essential nutrients from fresh unprocessed food, you will reverse years of damage in your arteries and throughout your body from consuming the typical American diet.”

It probably comes as no surprise that Lundell has been portrayed as a quack by the mainstream medical establishment. The main argument to back up his “quackery” was that his medical license was revoked in 2008…although the man was already retired and had no plans to return to the surgery room. He was not called a quack when he was performing surgeries, but once he took his 25 years of practice and discerned what he believes is the cause of heart disease, it was then that he was attacked by his peers. Which brings up the question if Lundell came onto the American Medical Association’s radar as he was working on and promoting his book, The Cure for Heart Disease, which was published in 2007.

Millions of dollars are made from heart disease treatment and statin medications. This established industry does not want anyone to interfere. Lundell said it himself, “Deviations from these recommendations were considered heresy and could quite possibly result in malpractice.” And it sure is easier to discredit a retired heart surgeon and chief of surgery with 25 years of experience if you revoke his license.

Dr. Dwight Lundell’s full statement, here

About the Author

Alex Pietrowski is an artist and writer concerned with preserving good health and the basic freedom to enjoy a healthy lifestyle. He is a staff writer for WakingTimes.com and an avid student of Yoga and life.

Image Source: http://www.bbc.com/news/health-27423152

from:    http://www.wakingtimes.com/2015/10/06/prestigious-heart-surgeons-confession-reveals-the-truth-about-heart-disease/

Serrapeptase & Your Health

Serrapeptase: an Enzyme That Treats Inflammation, Arthritis, Scar Tissue and More

Serrapeptase an Enzyme You Should Not Be Without

14th August 2015

By Dr. Michelle Kmiec

Contributing Writer for Wake Up World

The use of enzymes therapeutically is not a new concept, and has been widely accepted for its healing properties in both traditional and modern medicine.

Serrapeptase is a proteolytic enzyme, which means that it breaks down protein into smaller components (peptides and amino acids) that the body can re-use. It is derived from the digestive system of the silk worm, which regurgitates serrapeptase to break free from its cocoon.

Scientists in India first began to research the enzyme to see how it could be used therapeutically in the human body. From the start, they were astonished to realize that serrapeptase is a very powerful anti-fibrotic enzyme, with applications for the treatment of  inflammation, arthritis, scar tissue and much more.

What Does Serrapeptase Do?

Realizing that serrapeptase is anti-fibrotic was an interesting discovery because many health conditions are the result of abnormal thickening or scarring of fibrous connective tissue, a condition known as fibrosis.

Fibrosis is any disease where excess fibrous growth is present. This includes a wide range of conditions and health issues, including the following:

  • Plaquing of the arterial walls (atherosclerosis)
  • Fibrocystic breasts
  • Uterine fibroid tumors
  • Scarring after injury
  • Scarring after surgery
  • Cystic Fibrosis; affecting the exocrine glands (secreting glands; mucus, hormones, etc.) of the lungs, liver, pancreas, and intestines.
  • Blood clots; due to the fibrin in blood

The action of serrapeptase doesn’t stop there. It is an effective enzyme against inflammation in all its forms. In other words, inflammation of the joints, the digestive system as well as other organs.

This is because serrapeptase breaks down the dead tissues and excess fibrin, thus eliminating the body’s defense mechanism which is known as inflammation. The body is then able to clean out the burdensome dead tissues and fibrin growths, allowing for the healing process to begin more effectively.

Inflammatory health conditions that serrapeptase is effective against are:

  • Ulcerative Colitis
  • Crohn’s Disease
  • Irritable Bowel Syndrome (IBS)

Serrapeptase, by helping the body eliminate dead tissues and fibrin growths, is extremely beneficial to those suffering from autoimmune disorders such as:

  • Multiple Sclerosis
  • Rheumatoid Arthritis
  • Psoriasis
  • Allergies
  • Cancer

Serrapeptase in these cases, not only breaks down the dead fibrin tissues, but also serve as a healthy alternative to NSAIDS (aspirin, ibuprofen), and powerful steroids that are sometimes used for pain control.

Conditions That Have Been Helped by Serrapeptase

  • Pain (of all kinds)
  • Arthritis
  • Arterial plaque
  • Headaches caused by inflammation
  • Multiple Sclerosis
  • Lupus
  • Rheumatoid Arthritis
  • Psoriasis
  • Emphysema
  • Bronchitis
  • Pulmonary Tuberculosis
  • Asthma
  • Sinusitis
  • Eye conditions caused by inflammation
  • Injuries and trauma
  • Post operative scarring
  • Inflammatory bowels diseases
  • Cystitis
  • Fibroid tumors
  • Fibromyalgia
  • Fibrocystic diseases
  • Varicose Veins
  • Cardiovascular diseases
  • Subclinical chronic inflammation; premature aging

Dosages

Regarding the conversion of mg and IU for serrapeptase, the answer is not that easy. There appears to be a different standard of conversion depending on what company you choose to buy from. There is some research that has used the ratio of mg of serrapeptase which equals 20,000 units of activity, however not exclusively.

There has also been research done with 200 mg or 20,000 IU.

With this in mind, it would be best to not try to compare the two, but rather stick to one measurement or another.

The dosage varies depending on the condition you are trying to address or if you are simply using the enzyme for maintenance purposes.

Dosages range from:

  • 30 mg – 1000 mg
  • 10,000 IU – 100, 000 IU

In either case, taking 1 – 2 per day is typical for maintenance or for minor ailments. The therapeutic dosage can be as high as taking the max dosage (either 1000 mg or 100,000 IU. Keep in mind that this does not mean that they are equivalent) for up to 30 pills per day for the lower potency and dosages taken 1 -2 times per day for the higher range.

There doses seem to be the concern regarding the “blood thinning” properties of serrapeptase, so let’s clarify what is really meant by blood thinners.

Technically, the blood cannot get “thin”. What happens when you take something that acts to “thin the blood”, like an Aspirin or something stronger such as Coumadin, is that the blood becomes less sticky, so the blood can then flow more freely. The blood itself has not changed, but rather the mechanism that allows (or disallows) for free flow has. This is a subtle concept, but an important one.

There are many things that can impede blood flow such as:

  • Platelets sticking together
  • Clotting
  • Plaquing
  • Inflammation

With the use of serrapeptase, any of the above can be remedied and the research has proven it. However, the question is…will serrapeptase interfere with a drug therapy being used to “thin the blood”?

There appears to be no concerns with taking serrapeptase at the lower dosages. The really cool thing about this enzyme is that whether you take lower doses or higher doses, you will ultimately achieve the same effect. One just takes a bit longer than the other.

If you are concerned regarding any interactions, please consult a knowledgeable doctor. I say knowledgeable because this enzyme has a great deal of research supporting it, so if your current doctor dismisses the idea of trying serrapeptase, he/she is giving an opinion without having read the research. If that is the case, please seek out a healthcare professional who is open to all methods of healing — especially non-pharmaceutical methods that have been shown to be effective for your overall health!

Remember, there is only one you… it is your right to be in control of your health!

frm:    http://wakeup-world.com/2015/08/14/serrapeptase-enzyme-treats-inflammation-arthritis-scar-tissue-more/

Garlic & Inflammation

Garlic Prevents Inflammation, a Cause of Varicose Veins. How to Make Garlic Oil.

Screen Shot 2015-02-12 at 11.51.23 AM

Many Americans have some form of varicose veins.  Processed food,  lack of physical activity, obesity, nutritional deficiencies and prolonged sitting or standing can burden the veins.

Varicose veins are blood vessels that have become enlarged and tortuous. Varicose veins usually happen in the legs and is associated with chronic inflammation and poor circulation. You must de-flame the body to reduce and eliminate varicose veins.  Garlic is a great remedy for varicose veins. It can break down the protein content in the body and distribute it evenly. This increases the protein supply to the lower limb region.

How to make Garlic oil to Treat Varicose Veins Naturally

Ingredients:

  • 5 cloves of garlic
  • 3 oranges
  • 2 tablespoons olive oil

Finely slice 6 cloves garlic, put them in a clean jar with lid, then add the juice of 3 oranges and  2 tablespoons olive oil

Allow to  sit for 12 hours before you use it.

Shake well before use

In the evening, pour several  drops of garlic mixture on fingers, and rub it on the areas of concern  with a circular motion.  Put a plastic bag and wrap the legs with bandage or a warm cloth. Repeat every night.

from:    http://livingtraditionally.com/garlic-prevents-inflammation-cause-varicose-veins-make-garlic-oil/#more-5313

On Diet & Treatment

 

 

Pharmacy Exposed: The Most Dangerous and Over-Prescribed Medications

Written By:

Rob Kress, RPh

Pharmacy Exposed: The Most Dangerous and Over-Prescribed Medications

As a pharmacist I am very encouraged with the growing sentiment of our culture, that yes, we are in an over-medicated society, and medications are often unnecessarily prescribed and don’t come without consequences.

 “The significant problems we face today cannot be solved at the same level of thinking we were at when we created them.”

-Albert Einstein

I like to believe that we are heading towards the different levels of thinking to avoid what I believe is the next great issue of our time – being poisoned by pharmaceutical drugs. So let’s begin rethinking some of the pro-pharma practices which are taking us in this direction.

In a previous article I spoke of the 100 year haul of industrialized medicine, and how we need to approach health care from a different perspective. Part of this new approach must be related to shunning the narrow minded symptom management approach of prescription therapy, avoid treating side-effects of medications with more medications, while searching to address the root cause.

I firmly believe that the majority of medications prescribed today could be avoided via diet, lifestyle, mind-body, and natural medicine. This would avoid the side-effects, drug-to-drug interactions, drug induced nutrient depletions, and the financial drain that comes with uncontrolled prescribing of medication therapy.

Where there are thousands of drugs on the market, in the coming posts I am going to focus on what I believe are some of the worst offenders based on how common they are utilized and the problems they can lead to. Of course there are valid indications where drug use is appropriate and needed, although what I will be delving into are the instances of over-used medications in which there are often better options.

Medications can be sneaky, they might not cause a major side-effect now, and instead they whittle away, weaken your body, opening the door to a cascade of health issues.

The first class of drugs I want to speak about is in the family of antacids, Proton Pump Inhibitors (PPI’s.) You will recognize the family of proton pump inhibitors by medications such as Prilosec, Prevacid, Nexium, Protonix, Dexilant and others. These can be found in both over the counter and prescription medications.

Acid reflux and heartburn are very common complaints that lead to countless doctors’ visits, missed days of work, and billions of dollars spent in diagnosis and treatment, much of which could be avoided.

In allopathic medicine the standard answer to treating acid reflux has been to neutralize, reduce, or block the natural hydrochloric acid (HCL) production in the body, and PPI’s are often the first line of treatment.

Proton pump inhibitors inhibit the production and release of hydrochloric acid, thus drastically wiping a needed acidic environment, which plays a critical role in digestive health. This might serve a short term purpose in healing or reducing the irritation of an ulcer, although an acid free environment is not how your digestive tract is designed to operate.

A symptom such as acid reflux is often a sign of a greater problem brewing, and thus by quieting the symptom you could be ignoring a much greater issue, or even creating a new one.

What many people do not realize is that a large portion of people who suffer from heartburn and acid reflux do so due to too little hydrochloric acid (HCL) production and secretion, not too much.  This is contrary to the commercials for the “purple pill”, and what I believe has become one of the biggest deceptions in marketing by mainstream medicine.

Hydrochloric acid production and secretion can be suppressed due to lifestyle, diet, and stress.  This is why the recommendation of taking apple cider vinegar often helps to relive acid reflux since we are adding an acid to the system. Not having enough hydrochloric acid can lead to insufficient digestion of foods, leading to the symptom of heartburn.
We need hydrochloric acid, it serves a great many purposes. Hydrochloric acid acts as a primary defense against food borne pathogens and helps promote a healthy microbial balance. (Good bacteria (probiotics) –vs. – yeasts, bad bacteria, and even parasites).

If we are low on hydrochloric acid production or secretion, we set the stage for infections to take over. This leads to the killing off or overwhelming the good bacteria in the digestive tract since good bacteria has trouble surviving the altered pH of an over-alkalinized environment. This opens the door for bad bacteria, yeasts, and molds to proliferate; thus you can see how long term antacid treatment could be adding insult to injury.

In fact, a recent study was released showing that proton pump inhibitors may increase the chance of Clostridum Difficile Diarrhea (Often referred to as C. Diff or CDAD) by 65%, and that’s when only taken for a few months.

In decreasing the hydrochloric acid, the use of proton pump inhibitors can lead to an inability to digest critical nutrients. Hydrochloric acid helps the body digest, absorb and assimilate proteins and calcium.  Proton pump inhibitors can also directly deplete nutrients including magnesium and vitamin B 12, which has lead researchers to suggest that long term use of PPI’s can influence or predispose someone to osteoporosis and cardiovascular disease.

What are the alternatives?

If you take an acid reducing or neutralizing medication under the direction of your physician, do not stop taking the drug without talking to your physician. Where I do believe there is a very real problem within the over-prescribing of such medications, in many instances they could have a valid indication, and discontinuing them can lead to a host of other problems.

There are a number of natural options for reflux and heartburn, as well as complementary therapies which we could look at for getting rid of bad organisms such as bacteria, viruses, yeast and parasites which don’t belong.  For this conversation I would like to stick with the foundational elements of (1) diet, (2) supporting the digestive process, (3) recolonizing good bacteria, (4) sooth and promote the integrity of the digestive lining, which can all help support common digestive symptoms of gas, indigestion, acid reflux, heartburn, diarrhea and constipation.

There are many dietary issues which can lead to the symptoms of heart burn, although I find that food intolerances and genetically modified foods (GMO’s) are two of the worst offenders for a wide array of digestive disorders. As far as intolerances go, you can have an intolerance or allergy to any food, although dairy and gluten are at the top of my list.

Glyphosate is the herbicide which is used on GMO seeds and it kills organisms such as weeds by disrupting what is known as the shikamate pathway which is present in plants and bacteria. The good bacteria that is in your gut also contains the shikamate pathway, and this is where GMO seeds can be detrimental to your digestive health. I have personally seen, when people incorporate a GMO free, all organic, plant heavy diet, issues of acid reflux can often disappear in just a few weeks.

Reason would suggest supplementing with hydrochloric acid (HCL), which is often a great option, although due to issues such as known or unknown digestive ulcers or even people taking medications such as anti-inflammatories and steroids, I like to consider a more conservative approach first.

In stimulating and supporting the digestive process we are looking at supplements such as digestive enzymes, including amylase, which helps digest sugars, protease to digest proteins, and lipase to help digests fats.

Recolonizing good bacteria through probiotics is imperative, even in a healthy digestive tract where symptoms are not prevalent.  I recommend high quality probiotics which have been tested to ensure that they will stick to the intestinal linings and actually colonize in the digestive tract.

To repair, sooth, and support the integrity there are a number of great natural ingredients including DGL (deglycyrrhizinated licorice), aloe, slippery elm, marshmallow root, and glutamine, to name a few. These ingredients can be found in combination or individual supplements, and as always, choose only high quality supplements from companies with transparency and integrity at their core

from:    http://www.greenmedinfo.com/blog/pharmacy-exposed-most-dangerous-and-over-prescribed-medications?page=2